PSMD10/Gankyrin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPSMD10/Gankyrin
Clone[4B5]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, k
FormatProtein A purified
Size0.05 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin, Western Blot (WB)
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DescriptionActs as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pahway, leading to prolonged AKT activation.
ImmunogenImmunogen: PSMD10 (AAH11960, 127 a.a. ~ 226 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Conjugation: Unconjugated
Other Names[Mouse [clone 3F6] (IgG1) to Human PSMD10/Gankyrin; PSMD10; 26s proteasome subunit 10; Ankyrin repeat protein; DJ889N15.2; Gankyrin; p28; p28(GANK)]
Gene, Accession #[PSMD10], Gene ID: 5716, NCBI: NP_002805.1, UniProt: O75832
Catalog #MBS2400906
Price$605
Order / More InfoPSMD10/Gankyrin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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