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Antigenic Specificity | PSMD10/Gankyrin |
Clone | [4B5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pahway, leading to prolonged AKT activation. |
Immunogen | Immunogen: PSMD10 (AAH11960, 127 a.a. ~ 226 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Conjugation: Unconjugated |
Other Names | [Mouse [clone 3F6] (IgG1) to Human PSMD10/Gankyrin; PSMD10; 26s proteasome subunit 10; Ankyrin repeat protein; DJ889N15.2; Gankyrin; p28; p28(GANK)] |
Gene, Accession # | [PSMD10], Gene ID: 5716, NCBI: NP_002805.1, UniProt: O75832 |
Catalog # | MBS2400906 |
Price | $605 |
Order / More Info | PSMD10/Gankyrin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |