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Antigenic Specificity | BRCC45 / BRE (Internal) IHC-plus |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, humanpredicted reactivity: bovine (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human BRCC45 / BRE. BRE Antibody, BRCA1-A complex subunit BRE Antibody, BRCC45 Antibody, BRCC4 Antibody Description: Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. |
Immunogen | Immunogen: BRCC45 / BRE antibody was raised against recombinant protein encompassing a sequence within the center region of human BRCC45. Immunogen Description: Recombinant protein encompassing a sequence within the center region of human BRCC45. Immunogen Type: Recombinant protein |
Other Names | [Rabbit (IgG) to Human BRCC45 / BRE; Human BRCC45 / BRE; BRCA1-A complex subunit BRE; BRCC4] |
Gene, Accession # | [BRCC45], Gene ID: 9577, NCBI: NP_004890.2, UniProt: Q9NXR7 |
Catalog # | MBS2400375 |
Price | $530 |
Order / More Info | BRCC45 / BRE (Internal) IHC-plus Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |