T-Cell Receptor gamma delta Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | T-Cell Receptor gamma delta |
| Clone | [11F2] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Flow Cytometry (FC), Immunohistochemistry (IHC) (frozen), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Clone 11F2 recognizes all molecular forms of the gamma/delta T-cell receptor (TCR) desribed so far. Two types of T cell antigen receptors (TCRs) are now known, the alpha/beta, and the gamma/delta heterodimer, which are expressed at the cell surface in association with the CD3 molecular complex. TCR-gamma can occur in either disulphide-linked or non-disulphide-linked forms. The gamma/delta T-cell receptor is present on a minor subset of T lymphocytes in peripheral blood, thymus, spleen, and lymph node. In man and Mouse, only a small part of the T lymphocytes of the peripheral blood (<5%) is gamma/delta. gamma/delta T lymphocytes may complement alpha/beta T cells in terms of antigenic specificities, functional capabilities, or si |
| Immunogen | Product Type: Primary Antibodies. Source: 11F2 (anti-TCR gamma delta-l) is a Mouse monoclonal IgG1 antibody derived by fusion of SP2/0-Ag14 Mouse myeloma cells with spleen cells from a Balb/c mice immunized with protein A-Sepharose/anti-CD3/antigen complex. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS570229 |
| Price | $415 |
| Order / More Info | T-Cell Receptor gamma delta Antibody from MYBIOSOURCE INC. |
| Product Specific References | Borst, J., Van Dongen, J., Bolhuis, R., Peters, P., Hafler, D., De Vries, E., Van de Griend, R. (1988). Distinct molecular forms of Human T cell receptor g/d detected on viable T cells by a monoclonal antibody. I. Exp. Med 167 1626-1644 Vroom, T., Scholte, G., Ossendorp, F., Borst, J. (1991). Tissue distribution of Human g/d T cells: No evidence for general epithelial tropism. J. Clon. Pathol. 44 1012-1017 Bos, J.D., Teunissen, M.B.M., Cairo, I., Krieg, S.R., Kapsenberg, M.L., Das, P.K., and Borst, J. (1990). T-cell receptor gamma delta bearing cells in normal Human skin J. Invest. Dermatol. 94: 37-42. Lanier, L., Ruitenberg, J., Bolhuis, R., Borst, J., Phillips, J., Testi, R. (1988). Structural and serological heterogeneity of g/d T cell antigen receptor expression in thymus and peripheral blood. Eur J Immunol. 18 1985-1992 Lanier, L, Serafini, A., Ruitenberg, J., et all. (1987) The gamma T-cell antigen receptor. J Clin Immunol. 7 429 Testi, R., Lanier, L. (1989). Functional expression of CD28 on T cell antigen receptor g/d-bearing T lymphocytes. Eur J Immunol 19 185 Lanier, L., Federspiel, N., Ruitenberg, J., Phillips, J., Allison, J., Weiss, A. (1987(. The T cell antigen receptor complex expressed on normal peripheral blood CD4--, CD8- T lymphocytes: A CD3-associated disulfide-linked g chain heterodimer. J Exp Med 165 1076-1094. Voogt, P., Falkenburg, J., Fibbe, W., et al. (1989). Normal hematopoietic progenitor cells and malignant lymphohematopoietic cells show different susceptibility to direct cell-mediated MHC-non-restricted lysis by T cell receptor-/CD3-, T cell receptor gd /CD3 and T cell receptor-alpha/beta /CD3 lymphocytes 142 1774-1780. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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