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Antigenic Specificity | P-glycoprotein 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: P-glycoprotein 1 Polyclonal Antibody detects endogenous levels of P-glycoprotein 1 protein. The membrane-associated protein encoded by ABCB1 (ATP binding cassette subfamily B member 1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by ABCB1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumul |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human P-glycoprotein 1 |
Other Names | [Rabbit P-glycoprotein 1; ABCB1; MDR1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243] |
Gene, Accession # | [PGY1], Gene ID: 5243, NCBI: NP_000918.2, UniProt: P08183 |
Catalog # | MBS9706215 |
Price | $130, $220, $325 |
Order / More Info | P-glycoprotein 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |