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Antigenic Specificity | SCN4B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SCN4B antibody detects endogenous levels of total SCN4B. Function: Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the suceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom.Subunit Structure: Component of the voltage-sensitive sodium channel complex that consists of an ion-conducting pore-forming alpha subunit and one or more regulatory beta subunits. Heterooligomer with SCN2A; disulfide-linked.Post-translational Modifications: Contains an interchain disulfide bond with SCN2A. N-glycosylated.Similarity |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane Tissue Specificity: Expressed at a high level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart. Expressed in the atrium. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%) |
Other Names | [SCN4B_HUMAN; Sodium channel subunit beta-4] |
Gene, Accession # | [SCN4B], Gene ID: 6330, NCBI: NP_001135820.1, UniProt: Q8IWT1 |
Catalog # | MBS9605966 |
Price | $240, $280 |
Order / More Info | SCN4B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |