SETDB1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySETDB1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
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DescriptionThe Erg-associated protein with SET domain (ESET), also known as SET-domain, bifurcated 1 (SETDB1) protein, is a member of a family of histone lysine methyltransferases, each of which contains a conserved catalytic SET domain originally identified in Drosophila Su[var]3-9, Enhancer of zeste, and Trithorax proteins (1). ESET also contains tudor and methyl-CpG-binding domains, which may coordinate binding to methylated histones and methylated DNA, respectively (1). ESET methylates histone H3 Lys9, creating a transcriptionally repressive mark that facilitates gene silencing (1-3). However, unlike SUV39H histone H3 Lys9 methyltransferases, which function mainly in heterochromatin regions such as pericentric heterochromatin, ESET functions mainl
ImmunogenImmunogen: Recombinant Protein
Other Names[ESET; H3-K9-HMTase4; KG1T; KIAA0067; KMT1E], [SETDB1; SETDB1; ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4; KIAA0067; KMT1E; ESET; H3-K9-HMTase 4]
Gene, Accession #[SETDB1], Gene ID: 9869, NCBI: Q15047.1, UniProt: Q15047
Catalog #MBS126067
Price$235, $350
Order / More InfoSETDB1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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