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Antigenic Specificity | JAM-C, Mouse |
Clone | JAM-C |
Host Species | Mouse |
Reactive Species | reactivity: mouse. cross reactivity: human |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | F, Flow Cytometry (FC/FACS), FS, Immunoassay (IA), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Product Description: The monoclonal antibody CRAM-18 F26 recognizes junctional adhesion molecule-C (JAM-C) also known as JAM-2, a 45 kD cell adhesion molecule (CAM). JAM-C is a transmembrane protein which is a member of the immunoglobulin superfamily found at intercellular junctions of endothelial cells. JAM-C belongs together with JAM-A (JAM or JAM-1) and JAM-B (VE-JAM or JAM-3) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. JAM-C is potentially involved in the junctional sealing of the |
Immunogen | n/a |
Other Names | [junctional adhesion molecule C isoform 2; Junctional adhesion molecule C; junctional adhesion molecule C; junctional adhesion molecule 3; JAM-2; Junctional adhesion molecule 3; JAM-3], [JAM3; JAM3; JAMC; JAM-2; JAM-3; JAM-C; UNQ859/PRO1868; JAM-C; JAM-3] |
Gene, Accession # | [JAM-C], Gene ID: 83700, NCBI: NP_001192258.1 |
Catalog # | MBS584389 |
Price | $520 |
Order / More Info | JAM-C, Mouse Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Aurrand-Lions, M et al; JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells. J Biol Chem 2001, 276: 2733 2. Aurrand-Lions, M et al; Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members. Blood 2001, 98: 3699 3. Johnson-Leger, C et al; Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration. Blood 2002, 100: 2479 |