PRMT1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPRMT1
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg, 0.1 mg
Concentrationn/a
ApplicationsChromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB)
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DescriptionArginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Together with dimethylated PIAS1, represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. May be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite out
ImmunogenImmunogen: A synthesized peptide derived from human PRMT1. Subcellular Localization: Nucleus. Nucleus, nucleoplasm. Cytoplasm, cytosol. Mostly found in the cytoplasm. Colocalizes with CHTOP within the nucleus. Low levels detected also in the chromatin fraction (By similarity). Tissue Specificity: Widely expressed.
Other Names[Protein arginine N-methyltransferase 1; 2.1.1.319; Histone-arginine N-methyltransferase PRMT1; Interferon receptor 1-bound protein 4; PRMT1; HMT2; HRMT1L2; IR1B4], [PRMT1; PRMT1; ANM1; HCP1; IR1B4; HRMT1L2; HMT2; HRMT1L2; IR1B4]
Gene, Accession #[PRMT1], Gene ID: 3276, NCBI: NP_001527.3, UniProt: Q99873
Catalog #MBS179650
Price$160, $340, $340
Order / More InfoPRMT1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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