CD46 (Membrane Cofactor Protein) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD46 (Membrane Cofactor Protein) |
| Clone | [169-1-E4.3] |
| Host Species | Mouse |
| Reactive Species | human, baboon. does not react with horse. |
| Isotype | IgG2a, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of 52kDa-58kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria. |
| Immunogen | Immunogen: Stimulated human leukocytes |
| Other Names | [AHUS2; Complement membrane cofactor protein; MCP; Measles virus receptor; Membrane cofactor protein; MIC10; TLX; Trophoblast leucocyte common antigen; Trophoblast lymphocyte cross reactive antigen], [CD46; CD46; MCP; TLX; AHUS2; MIC10; TRA2.10; MCP; MIC10] |
| Gene, Accession # | [CD46], Gene ID: 4179, NCBI: NP_002380.3, UniProt: P15529 |
| Catalog # | MBS439572 |
| Price | $190, $340, $340 |
| Order / More Info | CD46 (Membrane Cofactor Protein) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sparrow et al. Human Immunol 7, 115 (1983). Purcell et al. Immunol Cell Biol 67, 279289 (1989). Cho et al. Clin Exp Immunol 83, 257261 (1991). Purcell et al. Immunol 70, 155161 (1990) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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