LGR5 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LGR5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.05 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Polyclonal LGR5 antibody specific for Human LGR5. Biological Significance: LGR5 is a receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), LGR5 associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic devel |
| Immunogen | Immunogen: LGR5 antibody was raised in Rabbit using the peptide sequence around aa 490~494(K-I-S-N-Q) derived from Human LGR5(GPR49) as the immunogen. |
| Other Names | [Rabbit LGR5; LGR5; LGR5; LGR 5; LGR5; LGR-5; LGR 5; Leucine-rich repeat-containing G-protein coupled receptor 5; LGR-5; GPR49; GPR49; FEX] |
| Gene, Accession # | [LGR5], Gene ID: 8549, NCBI: O75473.1, UniProt: O75473 |
| Catalog # | MBS5309891 |
| Price | $295 |
| Order / More Info | LGR5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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