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Antigenic Specificity | TAB2 |
Clone | [3B5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. |
Immunogen | Immunogen: Purified recombinant fragment of human TAB2 expressed in E Coli. |
Other Names | [CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; TAB2], [CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; TAB2] |
Gene, Accession # | [TAB2], Gene ID: 23118, NCBI: NP_055908.1 |
Catalog # | MBS476088 |
Price | $335 |
Order / More Info | TAB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |