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Antigenic Specificity | Phospho-Ser515 Munc-18 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Specific for the ~65k Munc-18 protein phosphorylated at Ser515. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide. Affinity purified rabbit polyclonal antibody |
Immunogen | Antigen: Phosphopeptide corresponding to amino acid residues surrounding the phospho- Ser515 of Munc-18. Immunogen Information: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser515 conjugated to KLH. Immunogen Species: Rat |
Other Names | [syntaxin-binding protein 2; Syntaxin-binding protein 2; syntaxin-binding protein 2; unc-18B; unc18-2; munc18-2; unc-18 homolog 2; protein unc-18 homolog 2; protein unc-18 homolog B; syntaxin binding protein Munc18-2; syntaxin binding protein 2; Protein unc-18 homolog 2; Munc18-2; Unc18-2; Protein unc-18 homolog B], [Stxbp2; Stxbp2; Munc18b; Unc18b; Munc18-2; Unc18-2; Unc-18B] |
Gene, Accession # | [STXBP2], Gene ID: 81804, NCBI: NP_112388.1, UniProt: Q62753 |
Catalog # | MBS502078 |
Price | $360 |
Order / More Info | Phospho-Ser515 Munc-18 Antibody from MYBIOSOURCE INC. |
Product Specific References | • Ciufo LF, Barclay JW, Burgoyne RD, Morgan A (2005) Munc18-1 regulates early and late stages of exocytosis via syntaxin-independent protein interactions. Mol Biol Cell 16:470-482.• Liu J, Ernst SA, Gladycheva SE, Lee YY, Lentz SI, Ho CS, Li Q, Stuenkel EL (2004) Fluorescence resonance energy transfer reports properties of syntaxin1a interaction with Munc18-1 in vivo. J Biol Chem 279:55924-55936.• Sassa T, Ogawa H, Kimoto M, Hosono R (1996) The synaptic protein UNC-18 is phosphorylated by protein kinase C. Neurochem Int 29:543-552.• Sergio Leal-Ortiz, Clarissa L. Waites, Ryan Terry-Lorenzo, Pedro Zamorano, Eckart D. Gundelfinger, and Craig C. Garner (2008) Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis. J. Cell Biol., 181: 831 - 846. |