USP46 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityUSP46
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: USP46 antibody detects endogenous levels of total USP46. Function: Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67 (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:19075014, PubMed:26388029). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014).Subunit Structure: Interacts with WDR48 (PubMed:19075014, PubMed:26388029). Interacts with WDR20 (PubMed:20147737).Similarity: Belongs to the peptidase C19 family. USP12/USP46 subfamily.
ImmunogenImmunogen: A synthesized peptide derived from human USP46 Tissue Specificity: Broadly expressed. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken Similarity: Pig (100%), Zebrafish (80%), Bovine (100%), Horse (92%), Sheep (100%), Dog (100%), Chicken (100%)
Other Names[Deubiquitinating enzyme 46; FLJ11850; FLJ12552; FLJ14283; FLJ39393; Ubiquitin carboxyl terminal hydrolase 46; Ubiquitin carboxyl-terminal hydrolase 46; Ubiquitin specific peptidase 46; Ubiquitin specific processing protease 46; Ubiquitin specific protease 46; Ubiquitin thioesterase 46; Ubiquitin thiolesterase 46; Ubiquitin-specific-processing protease 46; UBP46_HUMAN; USP46]
Gene, Accession #[USP46], Gene ID: 64854, NCBI: NP_001127695.1, UniProt: P62068
Catalog #MBS9610306
Price$240, $280
Order / More InfoUSP46 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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