GABA B Receptor 1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | GABA B Receptor 1 |
| Clone | [S93A-49] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | APC-Cy7 conjugate |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~115 kDa. No cross-reactivity against GABA(B)R2. GABA (gamma-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B) and GABA(C) receptor. The ionotropic GABA(A) and GABA(C) receptors are ligand-gated ion channels that produce fast inhibitory synaptic transmission. In contrast, the metabotropic GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission (1). Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 where GABA(B)R1 binds the ligand and GABA(B)R2 is the primary G protein contact site (2). Two isoforms of GABA(B)R1 have been cloned: GABA(B)R1a is a 130 kD protein and GABA( |
| Immunogen | Immunogen: Fusion protein amino acids 873-977 (cytoplasmic C-terminus) of rat GABA(B)R1 |
| Other Names | [Mouse Rat GABA-B Receptor 1 IgG1; GABA-B Receptor 1 : APC/Cy7; GABA-B receptor 1; GABA-B-R1; GABR1_Human; Gamma aminobutyric acid receptor 1; GB1; GPRC3A] |
| Gene, Accession # | [GABR1], Gene ID: 81657, NCBI: NP_112290.2, UniProt: Q9Z0U4 |
| Catalog # | MBS8003112 |
| Price | $510 |
| Order / More Info | GABA B Receptor 1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Jones K.A,. et al. (2000) Neuropsychopharmacology 23: S41-9. 2. Duthey B., et al. (2002) J Biol Chem. 277: 3236-41. 3. Kaupmann K., et al. (1997) Nature 386: 239-46. |
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MYBIOSOURCE INC.
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