Ki67 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Ki67 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Ki67 antibody detects endogenous levels of Ki67. Description: KI-67 a protein that may be a marker of proliferating cells, involved in chromatin compaction. Its expression is altered in many tumor types including osteosarcomas, histiocytomas, prostate, breast and esophageal cancers. Mutated in colon, cervical and lung cancers.Function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electro |
| Immunogen | Immunogen: A synthesized peptide derived from human Ki67 Subcellular Location: Chromosome. Nucleus. Nucleus, Nucleolus. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the mitotic chromosome surface (PubMed:27362226). Associates with satellite DNA in G1 phase (PubMed:9510506). Binds tightly to chromatin in interphase, chromatin-binding decreases in mitosis when it associates with the surface of the condensed chromosomes (PubM |
| Other Names | [Antigen identified by Ki 67; Antigen identified by Ki-67; Antigen KI-67; Antigen KI67; Antigen Ki67; KI67_HUMAN; KIA; Marker of proliferation Ki-67; MIB 1; MIB; MKI67; PPP1R105; Proliferation marker protein Ki-67; Proliferation related Ki 67 antigen; Protein phosphatase 1 regulatory subunit 105; RP11-380J17.2] |
| Gene, Accession # | [Ki67], Gene ID: 4288, NCBI: NP_001139438.1, UniProt: P46013 |
| Catalog # | MBS9600136 |
| Price | $240, $280 |
| Order / More Info | Ki67 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zhu Y, Cai L, Guo J, Chen N, Yi X, Zhao Y, Cai J, Wang Z; Journal: Tumour Biol. Depletion of Dicer promotes epithelial ovarian cancer progression by elevating PDIA3 expression. Yang J, Ren X, Zhang L, Li Y, Cheng B, Xia J; Journal: Biomed Pharmacother. Oridonin inhibits oral cancer growth and PI3K/Akt signaling pathway. Chen G, Liang YX, Zhu JG, Fu X, Chen YF, Mo RJ, Zhou L, Fu H, Bi XC, He HC, Yang SB, Wu YD, Jiang FN, Zhong WD; Journal: Biomed Res Int. CC chemokine ligand 18 correlates with malignant progression of prostate cancer. Liu X, Huang YG, Jin CG, Zhou YC, Chen XQ, Li J, Chen Y, Li M, Yao Q, Li K, Lan M, Ye JG, Wang XC; Journal: Oncotarget. MicroRNA-370 inhibits the growth and metastasis of lung cancer by down-regulating epidermal growth factor receptor expression. Sun C, Huang C, Li S, Yang C, Xi Y, Wang L, Zhang F, Fu Y, Li D; Journal: Oncotarget. Hsa-miR-326 targets CCND1 and inhibits non-small cell lung cancer development. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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