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Antigenic Specificity | EPS15 (Phospho-Tyr849) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of EPS15 only when phosphorylated at tyrosine 849. This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.Wong W.T., Oncogene 9:1591-1597(1994).Bernard O.A., Oncogene 9:1039-1045(1994). |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 849 (S-A-Y(p)-P-S) derived from Human Ephrin EPS15. |
Other Names | [AF1P; MLLT5; EPS15; Protein Eps15] |
Gene, Accession # | [EPS15], Gene ID: 2060, NCBI: NP_001153441.1, UniProt: P42566 |
Catalog # | MBS9406781 |
Price | $200, $255 |
Order / More Info | EPS15 (Phospho-Tyr849) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |