Human ITGA2B Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human ITGA2B |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | DyLight 488 conjugate |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. It is mapped to 17q21.32. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. |
| Immunogen | Immunogen: E Coli-derived human ITGA2B recombinant protein (Position: L32-D263). |
| Other Names | [Rabbit IgG Human ITGA2B DyLight 488 Conjugated, Flow Validated; Integrin alpha-IIb; GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD41; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; ITGA2B; GP2B; ITGAB; Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)] |
| Gene, Accession # | [ITGA2B], Gene ID: 3674, NCBI: NP_000410.2, UniProt: P08514 |
| Catalog # | MBS1751305 |
| Price | $330 |
| Order / More Info | Human ITGA2B Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41). 2. Naik UP, Parise LV (1997). Structure and function of platelet alpha IIb beta 3.. Curr. Opin. Hematol. 4 (5): 317-22. 3. Quinn MJ, Byzova TV, Qin J et al. (2004). Integrin alphaIIbbeta3 and its antagonism.. Arterioscler. Thromb. Vasc. Biol. 23 (6): 945-52. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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