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Antigenic Specificity | NITEGE |
Clone | [BC-13] |
Host Species | Mouse |
Reactive Species | human, cow, dog, horse, porcine |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | 0.1 mg/mL |
Applications | Western Blotting, ELISA, IHC. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes the aggrecanase (ADAMTS-1, -4 & -5)-generated C-terminal neoepitope.TEGE after cleavage between amino acids.EGE373 and 374ARG. within the interglobular domain of aggrecanase-catabolised aggrecan (Human aggrecan sequence enumeration). Aggrecan monoclonal antibody to C-terminal neoepitope NITEGE (mouse, clone BC-13). This aggrecan degradation product usually remains within the tissue still complexed to hyaluronan and link protein. Its release from the cartilage usually signals that there has been extensive catabolism of aggrecan, which allows large complexes containing this metabolite to be released from the tissue. Overview: Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevi |
Immunogen | Immunogen: NITEGE synthetic peptide conjugate. Myeloma: x63-Ag8.653. Light Chain Type: kappa |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS442004 |
Price | $435 |
Order / More Info | NITEGE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |