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Antigenic Specificity | NCBP1 (C-term), 647-675 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.31 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This NCBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 647-675 amino acids from the C-terminal region of human NCBP1. The product of this gene is a component of the nuclearcap-binding protein complex (CBC), which binds to themonomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. Theencoded protein promotes high-affinity mRNA-cap binding andassociates with the CTD of RNA polymerase II. The CBC promotespre-mRNA splicing, 3'-end processing, RNA nuclear export, andnonsense-mediated mRNA decay. |
Immunogen | n/a |
Other Names | [Nuclear cap-binding protein subunit 1; 80 kDa nuclear cap-binding protein; CBP80; NCBP 80 kDa subunit; NCBP1; CBP80; NCBP] |
Gene, Accession # | [NCBP1], Gene ID: 4686, NCBI: NP_002477.1, UniProt: Q09161 |
Catalog # | MBS9204646 |
Price | $165, $370 |
Order / More Info | NCBP1 (C-term), 647-675 Antibody from MYBIOSOURCE INC. |
Product Specific References | Hwang, J., et al. Mol. Cell 39(3):396-409(2010) Kim, K.M., et al. Genes Dev. 23(17):2033-2045(2009) Dias, S.M., et al. Nat. Struct. Mol. Biol. 16(9):930-937(2009) Worch, R., et al. J. Mol. Biol. 385(2):618-627(2009) Ma, X.M., et al. Cell 133(2):303-313(2008) |