rat Cellular tumor antigen p53 Antibody from MYBIOSOURCE INC.

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Antigenic Specificityrat Cellular tumor antigen p53
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatfluorescein (FITC) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionActs as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression By similarity. Interacts with GRK5
ImmunogenImmunogen: Recombinant rat Cellular tumor antigen p53 protein
Other Names[Tumor suppressor p53; TP53], [Tp53; Tp53; p53; Trp53; P53]
Gene, Accession #[p53], Gene ID: 24842, NCBI: NP_112251.2, UniProt: P10361
Catalog #MBS719426
Price$160, $235
Order / More Inforat Cellular tumor antigen p53 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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