Edit |   |
---|---|
Antigenic Specificity | Bcl-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bcl-2 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Bcl-2 is the founding member of a family of over 20 proteins that are critical regulators of apoptosis. These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-2 is an inner mitochondrial membrane protein that inhibits apoptosis. It is thought to act by interacting with pro-apoptotic Bcl-2 family members such as Bak and Bad. Overexpression of Bcl-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer. |
Immunogen | Immunogen: Bcl-2 antibody was raised against a peptide corresponding to 14 amino acids near the middle of human Bcl-2. Buffer: Bcl-2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Bcl-2; Bcl-2; PPP1R50; Apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2], [BCL2; BCL2; Bcl-2; PPP1R50] |
Gene, Accession # | [BCL2], Gene ID: 596, NCBI: AAH27258, UniProt: P10415 |
Catalog # | MBS151006 |
Price | $375 |
Order / More Info | Bcl-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |