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Antigenic Specificity | CD5 (Mantle Cell Lymphoma Marker) |
Clone | [C5/473 + CD5/54/F6] |
Host Species | Mouse |
Reactive Species | human, rabbit, cow, rat |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malign |
Immunogen | Immunogen: Human CD5 recombinant protein (C5/473); A synthetic peptide from the intracellular region of human CD5 (CD5/54/F6) |
Other Names | [CD5 antigen (p56 62), LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, Lymphocyte glycoprotein T1/Leu1, T-cell surface glycoprotein CD5], [CD5; CD5; T1; LEU1; LEU1] |
Gene, Accession # | [CD5], Gene ID: 921, NCBI: NP_055022.2, UniProt: P06127 |
Catalog # | MBS438147 |
Price | $190, $340, $340 |
Order / More Info | CD5 (Mantle Cell Lymphoma Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Ferry JA et. al. American Journal of Clinical Pathology, 1996, 105(1):31-7. Gagneten D et. al. Diagnostic Cytopathology, 1996, 14(1):32-7 |