Tyro3 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Tyro3 |
| Clone | [1444CT895.86.31] |
| Host Species | Mouse |
| Reactive Species | mouse |
| Isotype | IgG1,k |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Tyro3 antibody is generated from a mouse immunized with a recombinant protein. Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated |
| Immunogen | n/a |
| Other Names | [Tyrosine-protein kinase receptor TYRO3; Etk2/tyro3; TK19-2; Tyrosine-protein kinase DTK; Tyrosine-protein kinase RSE; Tyrosine-protein kinase TIF; Tyro3; Dtk; Rse; Tif] |
| Gene, Accession # | [Tyro3], Gene ID: 22174, NCBI: NP_001277729.1, UniProt: P55144 |
| Catalog # | MBS9200143 |
| Price | $165, $370 |
| Order / More Info | Tyro3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Mark M.R.,et al.J. Biol. Chem. 269:10720-10728(1994). Crosier P.S.,et al.Growth Factors 11:125-136(1994). Lai C.,et al.Oncogene 9:2567-2578(1994). Fujimoto J.,et al.Oncogene 9:693-698(1994). Ohashi K.,et al.Oncogene 9:699-705(1994). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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