Tau, 4-repeat isoform RD4 (Tau Protein, Microtubule-associated Protein, MAP) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTau, 4-repeat isoform RD4 (Tau Protein, Microtubule-associated Protein, MAP)
Clone[4H380]
Host SpeciesMouse
Reactive Speciesmouse and bovine.
IsotypeIgG
Formatsupernatant
Size0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC). Other applications not tested
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DescriptionRecognizes human Tau (4-repeat isoform RD4), Mr 45-65kD. Higher MW band (68-72kD) represents phosphorylated Tau. Microtubule Associated Proteins (MAPS) bind to the tubulin subunits of microtubule structures and regulate their functional stability. In the cell MAPs bind to monomer and multimerized tubulin. MAP binding to multimerized tubulin further stabilizes the formation of higher order microtubulin structures. MAP binding to microtubule structures is mediated through phosphorylation through Microtubule Affinity Regulated Kinase (MARK). Phosphorylation releases MAPs bound to microtubules, destabilizing the structure, driving it toward disassembly. There are predominately two MAP types, I, II. Type II MAP includes MAP2, MAP4 and tau,and ar
ImmunogenImmunogen: Synthetic peptide corresponding to aa275-291, VQIINKKLDLSNVQSKC of human Tau (4-repeat isoform RD4) (Bovine thyroglobulin coupled). Region is flanking junction coded by adjacent exons 9 & 11 with the inclusion of exon 10.
Other Namesn/a
Gene, Accession #NCBI: NP_001116538
Catalog #MBS604301
Price$760
Order / More InfoTau, 4-repeat isoform RD4 (Tau Protein, Microtubule-associated Protein, MAP) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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