Human PDL-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human PDL-1 |
| Clone | [6A5] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | Protein G purified |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Reactive with human programmed death ligand-1 (PDL-1). Programmed Death Ligand-1 (PDL-1), a 40KD transmembrane protein, is a ligand of immune checkpoint protein Programmed Death-1 (PD-1). During T-cell receptor signalling, the binding of PDL-1 to PD-1 transmits an inhibitory signal to activated T-cells to decrease their proliferation. PDL-1 is also believed to play a role in the generation and regulation of Treg cells, and in the enhancement of Treg cell function. PDL-1/PD-1 pathway is important to immune suppression, such as self-tolerance, suppression of immune-rejection during pregnancy and allograft, and immune evasion by cancers. Upregulation of PD-L1 has been found to be associated with many cancer types. For example, increased PDL-1 |
| Immunogen | Immunogen: Human cell expressed recombinant PDL-1 (Phe19-Arg238) with poly-histidine tag at C-terminus. |
| Other Names | n/a |
| Gene, Accession # | [PDL-1] |
| Catalog # | MBS592434 |
| Price | $490 |
| Order / More Info | Human PDL-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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