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Antigenic Specificity | Human Pyruvate kinase PKM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. |
Immunogen | Immunogen: Recombinant human Pyruvate kinase PKM protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-65177 / sc-65178 / sc-65176 / sc-135048 / sc-292640 |
Other Names | [Cytosolic thyroid hormone-binding protein; CTHBP; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; THBP1; Tumor M2-PK; p58; PKM; OIP3; PK2; PK3; PKM2], [PKM; PKM; PK3; TCB; OIP3; PKM2; CTHBP; THBP1; HEL-S-30; OIP3; PK2; PK3; PKM2; CTHBP; OIP-3; THBP1] |
Gene, Accession # | [PKM], Gene ID: 5315, NCBI: NP_001193725.1, UniProt: P14618 |
Catalog # | MBS1489632 |
Price | $160, $235 |
Order / More Info | Human Pyruvate kinase PKM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |