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Antigenic Specificity | Human CD58 |
Clone | [8G24] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD58, also known as lymphocyte function-associated antigen (LFA-3) is a cell-bound immunoglobulin superfamily receptor with only one known ligand, CD2. CD58 is widely expressed on human hematopoietic and non-hematopoietic tissues, leukocytes, erythrocytes, endothelial and epithelial cells, and fibroblasts. The engagement of CD58 with CD2 optimizes immune recognition and initiates T cell expansion and activation. These contact activities can occur between helper T cells and antigen-presenting cells and cytolytic effectors and target cells. |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of CD58 extracellular domain (also called LFA-3). |
Other Names | [CD58; ag3; LFA3; LFA-3], [CD58; CD58; ag3; LFA3; LFA-3; LFA3; Ag3] |
Gene, Accession # | [CD58], Gene ID: 965, NCBI: NP_001138294.1, UniProt: P19256 |
Catalog # | MBS690932 |
Price | $490 |
Order / More Info | Human CD58 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |