FAS-L Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFAS-L
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsImmunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionThe antibody detects endogenous levels of FAS-L. FASLG is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in FASLG may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. FASLG (Fas Ligand) is a Protein Coding gene. Diseases associated with FASLG include Autoimmune Lymphoproliferative Syndrome and F
ImmunogenImmunogen: Synthesized peptide derived from part region of human FAS-L protein at amino acid sequence of 121-170
Other Names[Rabbit FAS-L; Tumor necrosis factor ligand superfamily member 6; Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD antigen CD178]
Gene, Accession #[FAS-L], Gene ID: 356, NCBI: NP_000630.1, UniProt: P48023
Catalog #MBS9709109
Price$130, $220, $325
Order / More InfoFAS-L Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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