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Antigenic Specificity | MAP3K5 |
Clone | [2E4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1, 374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase |
Immunogen | Immunogen: Purified recombinant fragment of human MAP3K5 expressed in E Coli. |
Other Names | [ASK1; MEKK5; MAPKKK5], [ASK1; MEKK5; MAPKKK5] |
Gene, Accession # | [MAP3K5], Gene ID: 26408, NCBI: AAI16629.1 |
Catalog # | MBS476181 |
Price | $335 |
Order / More Info | MAP3K5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |