Human ICOS Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human ICOS |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1k |
| Format | Protein A purified |
| Size | 0.1 mL |
| Concentration | 1ug/ul |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Antibody ANC6C6 binds to recombinant and cell surface ICOS. mAb name/Clone: ANC6C6The inducible costimulator (ICOS, T cell activation molecule H4) is similar to human CD28 (24% homology), and plays an analogous role in the T cell activation process. Secondary signaling through CD28 or ICOS results in discrete cytokine secretion profiles by the activated T cells.1 Signaling by either molecule is effectively down regulated by CD152 (CTLA-4) engagement.2 Human GL50 is a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2), and has been shown to be the ligand for ICOS.3 Two RNA splice variants exist for this molecule, differing only in the cytoplasmic domain. 4 Antibody ANC6C6 binds to recombinant ICOS-muI |
| Immunogen | Immunogen: Human HPB-MLT cells; human ICOS-muIg fusion protein |
| Other Names | [CD278] |
| Gene, Accession # | [ICOS] |
| Catalog # | MBS4159611 |
| Price | $540 |
| Order / More Info | Human ICOS Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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