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Antigenic Specificity | MESDC2 (C-term), 206-234 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.35 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MESDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the C-terminal region of human MESDC2. Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. |
Immunogen | n/a |
Other Names | [LDLR chaperone MESD; Mesoderm development candidate 2; Mesoderm development protein; Renal carcinoma antigen NY-REN-61; MESDC2; KIAA0081; MESD] |
Gene, Accession # | [MESDC2], Gene ID: 23184, NCBI: NP_055969.1, UniProt: Q14696 |
Catalog # | MBS9207546 |
Price | $165, $370 |
Order / More Info | MESDC2 (C-term), 206-234 Antibody from MYBIOSOURCE INC. |
Product Specific References | Murrills, R.J., et al. J. Cell. Biochem. 108(5):1066-1075(2009) Li, Y., et al. FEBS Lett. 580(22):5423-5428(2006) Veltman, I.M., et al. Hum. Mol. Genet. 14(14):1955-1963(2005) Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003) Hsieh, J.C., et al. Cell 112(3):355-367(2003) |