Rat Ephrin-A1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRat Ephrin-A1
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatbiotin conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionCell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which lea
ImmunogenImmunogen: Recombinant Rat Ephrin-A1 protein
Other Names[EPH-related receptor tyrosine kinase ligand 1; Immediate early response protein B61; Efna1; Epgl1; Lerk1], [Efna1; Efna1; B61; Epgl1; Lerk1; LERK-1]
Gene, Accession #Gene ID: 94268, NCBI: NP_446051.2, UniProt: P97553
Catalog #MBS1488309
Price$160, $235
Order / More InfoRat Ephrin-A1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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