NOC2L Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NOC2L |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: NOC2L antibody detects endogenous levels of total NOC2L. Function: Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53-and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter.Subunit Structure: Interacts with p53/TP53. Interacts (via the N-and C-terminus domains) with AURKB (via the middle kinase domain). Interacts with TP63 isoform TA*-gamma (via activati |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus > Nucleoplasm. Nucleus > Nucleolus. Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin-D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis. Tissue Specificity: Up-regulated by IL4 and CD40L in B-cells. Predicted Cross Reactivity: Pig, Bovine, Horse, S |
| Other Names | [NET15; NET7; NIR; NOC2 like; NOC2 like nucleolar associated transcriptional repressor; NOC2-like protein; NOC2L; NOC2L nucleolar associated transcriptional repressor; NOC2L_HUMAN; Novel INHAT (inhibitor of histone acetyltransferase) repressor; Novel INHAT repressor; Nucleolar complex associated 2 homolog (S. cerevisiae); Nucleolar complex protein 2 homolog; PPP1R112; Protein NOC2 homolog; Protein phosphatase 1 regulatory subunit 12] |
| Gene, Accession # | [NOC2L], Gene ID: 26155, NCBI: NP_056473.2, UniProt: Q9Y3T9 |
| Catalog # | MBS9605716 |
| Price | $240, $280 |
| Order / More Info | NOC2L Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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