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Antigenic Specificity | EED |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human EED. Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading totranscriptional repression of the affected target gene. Also recognizes'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark. |
Immunogen | Immunogen: Recombinant protein of human EED Conjugation: Unconjugated |
Other Names | [Rabbit (IgG) to Human EED; EED; Embryonic ectoderm development; HEED; WAIT1; WAIT-1; Polycomb protein EED] |
Gene, Accession # | [EED], Gene ID: 8726, NCBI: NP_001294936.1, UniProt: O75530 |
Catalog # | MBS2401936 |
Price | $530 |
Order / More Info | EED Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |