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Antigenic Specificity | Human CEACAM-1 (D1-4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, CEACAM-1 forms non-covalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice of CEACAM-1 variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist. |
Immunogen | Immunogen: Recombinant human sCEA-1 (D1-4). Preparation: Produced from sera of rabbits pre-immunized with highly pure (>95%) recombinant human soluble CEACAM-1 (D1-4). |
Other Names | [human CEACAM-1 (#D1-4); Carcinoembryo antigen-related cell adhesion molecule 1; CD66a], [CEACAM1; CEACAM1; BGP; BGP1; BGPI; BGP; BGP1; BGP-1] |
Gene, Accession # | [CEACAM-1 (D1-4)], Gene ID: 634, NCBI: NP_001192273.1, UniProt: P13688 |
Catalog # | MBS691208 |
Price | $390 |
Order / More Info | Human CEACAM-1 (D1-4) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Beauchemin et al, Exp Cell Res 252 (1999) 2. Thompson et al, Genomics 12 (1992) 3. Waggener and Ergun, Exp Cell Res 261 (2000) 4. Barnett et al, J Cell Biol 108 (1989) 5. Hinoda et al, Proc Natl Acad Sci 85 (1998) 6. Muller et al, Blood 105 (2006) 7. Kilic et al, Blood 110 (2007) 8. Zengin et al, Development 133 (2006) 9. Oliveira-Ferrer et al, Cancer Res 64 (2004) |