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Antigenic Specificity | BAX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BAX (NP 620116.1). |
Other Names | [BCL2L4] |
Gene, Accession # | [BAX], Gene ID: 581, NCBI: NP_004315.1, UniProt: Q07812 |
Catalog # | MBS8543935 |
Price | $280 |
Order / More Info | BAX Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |