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Antigenic Specificity | ENTPD5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono-or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 149-428 of human ENTPD5 (NP 001240.1). |
Other Names | [PCPH; CD39L4; NTPDase-5] |
Gene, Accession # | [ENTPD5], Gene ID: 957, NCBI: NP_001240.1, UniProt: O75356 |
Catalog # | MBS8547235 |
Price | $280 |
Order / More Info | ENTPD5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |