Phospho-VEGF Receptor 2 Antibody Sampler Kit Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-VEGF Receptor 2 Antibody Sampler Kit |
| Clone | n/a |
| Host Species | n/a |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 1 kit |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Vascular endothelial growth factor receptor 2 (VEGFR2, KDR, Flk-1) is a major receptor for VEGF-induced signaling in endothelial cells. Upon ligand binding, VEGFR2 undergoes autophosphorylation and becomes activated. Major autophosphorylation sites of VEGFR2 are located in the kinase insert domain (Tyr951/996) and in the tyrosine kinase catalytic domain (Tyr1054/1059). Activation of the receptor leads to rapid recruitment of adaptor proteins, including Shc, GRB2, PI3 kinase, NCK, and the protein tyrosine phosphatases SHP-1 and SHP-2. Phosphorylation at Tyr1212 provides a docking site for GRB2 binding and phospho- Tyr1175 binds the p85 subunit of PI3 kinase and PLCgamma, as well as Shb. Signaling from VEGFR2 is necessary for the |
| Immunogen | n/a |
| Other Names | [vascular endothelial growth factor receptor 2; Vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor 2; kinase insert domain protein receptor; Fetal liver kinase 1; FLK-1; Kinase NYK; Protein-tyrosine kinase receptor flk-1; CD_antigen: CD309] |
| Gene, Accession # | Gene ID: 16542, NCBI: NP_034742.2, UniProt: P35918 |
| Catalog # | MBS2550085 |
| Price | $265 |
| Order / More Info | Phospho-VEGF Receptor 2 Antibody Sampler Kit Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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