Human Histone H2A.x Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Histone H2A.x
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatcaprylic acid ammonium sulfate precipitate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.Histones are basic nucl
ImmunogenImmunogen: Recombinant human Histone H2A.x protein
Other Names[H2AFX; H2AX]
Gene, Accession #[H2AFX], Gene ID: 3014, NCBI: NP_002096.1, UniProt: P16104
Catalog #MBS7005116
Price$160, $235
Order / More InfoHuman Histone H2A.x Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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