IRS2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIRS2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman mouse rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: IRS2 Ab detects endogenous levels of total IRS2. Insulin Receptor Substrate 2 (IRS-2) is one of the major substrates of the insulin receptor kinase (1). In vertebrates, IRS-2 functions as a scaffolding protein to coordinate separate branches of the Insulin/IGF-signaling cascades (2). IRS-2 is essential for normal nutrient homeostasis because it mediates both peripheral insulin action and the effect of IGF-1 on B-cell growth. Mice lacking IRS-2 fail to maintain sufficient compensatory insulin secretion and develop diabetes as young adults
ImmunogenImmunogen: Recombinant protein of human IRS2 Subcellular Location: Cytoplasm > Cytosol
Other Names[Insulin Receptor Substrate 2; IRS 2;IRS2_HUMAN]
Gene, Accession #[IRS2], Gene ID: 8660, NCBI: NP_003740.2, UniProt: Q9Y4H2
Catalog #MBS9385623
Price$440, $715
Order / More InfoIRS2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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