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Antigenic Specificity | Vav2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Vav2 antibody detects endogenous levels of total Vav2. Function: Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity).Subunit Structure: Interacts (via SH2 domains) with the phosphorylated form of EPHA2. Interacts with SSX2IP (By similarity). Interacts with NEK3 and PRLR and this interaction is prolactin-dependent.Post-translational Modifications: Phosphorylated on tyrosine residues in response to FGR activation. |
Immunogen | Immunogen: A synthesized peptide derived from human Vav2 Tissue Specificity: Widely expressed. |
Other Names | [Guanine nucleotide exchange factor VAV2; Oncogene VAV2; Protein vav 2; VAV 2; Vav 2 oncogene; VAV-2; VAV2; VAV2 oncogene; VAV2_HUMAN] |
Gene, Accession # | [Vav2], Gene ID: 7410, NCBI: NP_001127870.1, UniProt: P52735 |
Catalog # | MBS9602271 |
Price | $240, $280 |
Order / More Info | Vav2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |