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Antigenic Specificity | MEN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MEN1 protein. Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression By similarity. May be involved in DNA repair.Chandrasekharappa S.C., Sci |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human MEN1. |
Other Names | [MEAI; Menin; SCG2; Wermer syndrome; Zollinger-Ellison syndrome] |
Gene, Accession # | [MEN1], Gene ID: 4221, NCBI: NP_000235.2, UniProt: O00255 |
Catalog # | MBS9404860 |
Price | $200, $255 |
Order / More Info | MEN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |