LDLR Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | LDLR |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.03 mL, 0.1 mL, 0.2 mL |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of LDLR protein. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in LDLR cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple |
| Immunogen | Immunogen: Synthesized peptide derived from part region of human LDLR protein at amino acid sequence of 540-620 |
| Other Names | [Rabbit LDLR; Low-density lipoprotein receptor; LDL receptor] |
| Gene, Accession # | [LDLR], Gene ID: 3949, NCBI: NP_000518.1, UniProt: P01130 |
| Catalog # | MBS9709667 |
| Price | $130, $220, $325 |
| Order / More Info | LDLR Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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