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Antigenic Specificity | GSK3 alpha |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GSK3 alpha antibody detects endogenous levels of total GSK3 alpha. Description: Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily, GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97% sequence similarity within their catalyti |
Immunogen | Immunogen: Purified recombinant fragment of human GSK3 alpha expressed in E. Coli Subcellular Location: Cytoplasmic and Nuclear |
Other Names | [DKFZp686D0638; Glycogen synthase kinase 3 alpha; Glycogen synthase kinase-3 alpha; GSK 3 alpha; GSK 3A; GSK-3 alpha; Gsk3a; GSK3A_HUMAN; GSK3alpha; Serine/threonine protein kinase GSK3A] |
Gene, Accession # | [GSK3A], Gene ID: 2931, NCBI: NP_063937.2, UniProt: P49840 |
Catalog # | MBS9602609 |
Price | $235, $295, $370 |
Order / More Info | GSK3 alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |