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Antigenic Specificity | Caspase-14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Caspase-14 Polyclonal Antibody detects endogenous levels of Caspase-14 protein. CASP14 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 14 has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of caspase 14 may be involved in keratinocyte terminal differentiation, which is im |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Caspase-14 at AA range: 110-190 |
Other Names | [Rabbit Caspase-14; Caspase-14; CASP-14] |
Gene, Accession # | [CASP14], Gene ID: 23581, NCBI: NP_036246.1, UniProt: P31944 |
Catalog # | MBS9700793 |
Price | $130, $220, $325 |
Order / More Info | Caspase-14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |