CLK2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCLK2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionDual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphorylates PPP2R5B thereby stimulating the assembly of PP2A phosphatase with the PPP2R5B-AKT1 complex leading to dephosphorylation of AKT1. Phosphorylates: PTPN1, SRSF1 and SRSF3. Regulates the alterna
ImmunogenImmunogen: Recombinant Human Dual specificity protein kinase CLK2 protein (240-499AA). Conjugate: Non-conjugated. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Species: Human. Research Area: Cell Biology. Target Names: CLK2
Other Names[Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2), CLK2], [CLK2; CLK2]
Gene, Accession #[CLK2], Gene ID: 1196, NCBI: NP_001281267.1, UniProt: P49760
Catalog #MBS1493273
Price$120, $160
Order / More InfoCLK2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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