MVP Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MVP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MVP antibody detects endogenous levels of total MVP. Description: This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.Function: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for prot |
| Immunogen | Immunogen: A synthesized peptide derived from human MVP Subcellular Location: Cytoplasm. Nucleus > Nuclear Pore Complex. 5% found in the nuclear pore complex. Translocates from the nucleus to the cytoplasm upon EGF treatment. Tissue Specificity: Present in most normal tissues. Higher expression observed in epithelial cells with secretory and excretory functions, as well as in cells chronically exposed to xenobiotics, such as bronchial cells and cells lining the intestine. Overexpressed in many m |
| Other Names | [LRP; Lung resistance related protein; Lung resistance-related protein; Major vault protein; Major vault protein, rat, homolog of; MVP; MVP_HUMAN; testicular secretory protein Li 30; VAULT 1; VAULT1] |
| Gene, Accession # | [MVP], Gene ID: 9961, NCBI: NP_001280133.1, UniProt: Q14764 |
| Catalog # | MBS9607388 |
| Price | $240, $280 |
| Order / More Info | MVP Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zhou H, Lin C, Zhang Y, Zhang X, Zhang C, Zhang P, Xie X, Ren Z; Journal: Cell Prolif. miR-506 enhances the sensitivity of human colorectal cancer cells to oxaliplatin by suppressing MDR1/P-gp expression. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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