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Antigenic Specificity | MMP3 |
Clone | [rMMP3/1730] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and hea |
Immunogen | Immunogen: Recombinant fragment of human MMP3 (around aa 317-327) Cellular Localization: Cytoplasm, extracellular matrix. |
Other Names | [CHDS6; Matrix metalloproteinase 3; Matrix metalloproteinase-3; MGC126102; MGC126103; MGC126104; MMP 3; MMP-3; MMP3; Proteoglycanase; SL-1; SL1; STMY; STMY1; STR1; Stromelysin 1; Stromelysin-1; Transin 1] |
Gene, Accession # | [MMP3], Gene ID: 4314, NCBI: NP_002413.1, UniProt: P08254 |
Catalog # | MBS4380111 |
Price | $190, $340, $340 |
Order / More Info | MMP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | Shur, S.A., et al. 1983. The role of cysteinyl residues in the phosphorylase kinase activity as revealed by iodacetamide modification. Biochem. Int. 7: 197-206 |