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Antigenic Specificity | GABARAP (N-term), 1-30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, rabbit, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This GABARAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GABARAP. Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. GABARAP is GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. |
Immunogen | n/a |
Other Names | [Gamma-aminobutyric acid receptor-associated protein; GABA(A) receptor-associated protein; MM46; GABARAP; FLC3B] |
Gene, Accession # | [GABARAP], Gene ID: 11337, NCBI: NP_009209.1, UniProt: O95166 |
Catalog # | MBS9204011 |
Price | $165, $370 |
Order / More Info | GABARAP (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
Product Specific References | References for protein: 1.Nemos, C., et al., Brain Res. Mol. Brain Res. 119(2):216-219 (2003). 2.Stangler, T., et al., J. Biol. Chem. 277(16):13363-13366 (2002). 3.Knight, D., et al., J. Biol. Chem. 277(7):5556-5561 (2002). 4.Tanida, I., et al., J. Biol. Chem. 277(16):13739-13744 (2002). 5.Harris, R., et al., J. Biomol. NMR 21(2):185-186 (2001). References for U251 cell line: 1. Westermark B.; Ponten J.; Hugosson R. (1973). Determinants for the establishment of permanent tissue culture lines from human gliomas. Acta Pathol Microbiol Scand A. 81:791-805. [PMID: 4359449]. 2. Ponten, J.,Westermark B. (1978). Properties of Human Malignant Glioma Cells in Vitro. Medical Biology 56: 184-193.[PMID: 359950]. 3. Geng Y.;Kohli L.; Klocke B.J.; Roth K.A.(2010). Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent. Neuro Oncol. 12(5): 473-481.[ PMID: 20406898]. |