GABARAP (N-term), 1-30 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGABARAP (N-term), 1-30
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: bovine, mouse, rabbit, rat)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsImmunofluorescence (IF), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionThis GABARAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GABARAP. Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. GABARAP is GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.
Immunogenn/a
Other Names[Gamma-aminobutyric acid receptor-associated protein; GABA(A) receptor-associated protein; MM46; GABARAP; FLC3B]
Gene, Accession #[GABARAP], Gene ID: 11337, NCBI: NP_009209.1, UniProt: O95166
Catalog #MBS9204011
Price$165, $370
Order / More InfoGABARAP (N-term), 1-30 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesReferences for protein: 1.Nemos, C., et al., Brain Res. Mol. Brain Res. 119(2):216-219 (2003). 2.Stangler, T., et al., J. Biol. Chem. 277(16):13363-13366 (2002). 3.Knight, D., et al., J. Biol. Chem. 277(7):5556-5561 (2002). 4.Tanida, I., et al., J. Biol. Chem. 277(16):13739-13744 (2002). 5.Harris, R., et al., J. Biomol. NMR 21(2):185-186 (2001). References for U251 cell line: 1. Westermark B.; Ponten J.; Hugosson R. (1973). Determinants for the establishment of permanent tissue culture lines from human gliomas. Acta Pathol Microbiol Scand A. 81:791-805. [PMID: 4359449]. 2. Ponten, J.,Westermark B. (1978). Properties of Human Malignant Glioma Cells in Vitro. Medical Biology 56: 184-193.[PMID: 359950]. 3. Geng Y.;Kohli L.; Klocke B.J.; Roth K.A.(2010). Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent. Neuro Oncol. 12(5): 473-481.[ PMID: 20406898].
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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