Human Bestrophin Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human Bestrophin antibody, protein, ELISA kits.
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| Antigenic Specificity | Human Bestrophin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | DyLight 488 conjugate |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Bestrophin-1 (Best1) is a protein that, in humans, is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular d |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human Bestrophin (RFIYRLALTEEQQLMFEKLTLYCD). |
| Other Names | [Rabbit IgG Human Bestrophin DyLight 488 Conjugated, Flow Validated; Bestrophin-1; TU15B; Vitelliform macular dystrophy protein 2; BEST1; VMD2; Bestrophin 1] |
| Gene, Accession # | [BEST1], Gene ID: 7439, NCBI: NP_001132915.1, UniProt: O76090 |
| Catalog # | MBS1751347 |
| Price | $330 |
| Order / More Info | Human Bestrophin Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: BEST1 bestrophin 1. 2. Johnson AA, Guziewicz KE, Lee CJ, Kalathur RC, Pulido JS, Marmorstein LY, Marmorstein AD (January 2017). Bestrophin 1 and retinal disease. review. Progress in Retinal and Eye Research. 58: 45-69. |
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MYBIOSOURCE INC.
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